Academic Staff

  3 Jan 2018

Ugbogu, Eziuche Amadike

  Rank: Senior Lecturer


Qualifications:  B.Sc, M.Sc. Biochemistry (ABSU), Dip, M.Sc., Food Science and Nutrition, PhD, Biochemistry (Heriot-Watt University, UK)


Contact address:  Department of Biochemistry, Abia State University P.M.B 2000, Uturu, Abia State, Nigeria.


Email address:


Scholarship: Commonwealth Scholarship

TETfund sponsorship


Membership of Scientific Societies

Biochemical Society, United Kingdom

The Nutrition Society, United Kingdom

Genetic Society of America (GSA)

American Association for the Advancement of Science (AAAS)

Nigerian Society of Biochemistry and Molecular Biology (NSBMB)




University Committee Membership

  1. Member, Abia State University book review committee
  2. Member, Abia State University integrated farm business investment
  3. Member/Secretary Abia State University Ad Hoc bank partnership committee


  1. Member, Abia State University Review panel on the dismissal of an aggrieved staff.


  1. Member, Abia State University Time-Table Committee


  1. Member/Secretary, Abia State University Committee for Research and Intellectual Development (CRID).


  1. Member, Abia State University Website Review Committee
  2. Member, Student Union Government Electoral Committee (SUGECO)
  3. Taskforce for addressing the issue of students without matriculation number from 200 level upwards


Administrative position

Head of Department of Biochemistry 2016-2017 academic session and successfully led the department to obtain full NUC accreditation.


Public service

Returning Officer, Isiala Ngwa North L.G.A

Jaja Nwachukwu Hall Master, Abia State University





Current area of Research

  • To evaluate biochemical significance and toxicological effects of medicinal plants native to Nigeria.
  • By means of biochemical and genetic approaches, to gain insight into how the Prs complexes contribute to cell metabolism and interact with the cell integrity pathway.
  • To investigate the effectiveness of the use of enzymes and plant extracts in reducing greenhouse gas emission from livestock production.


Research Grants

  1. Anti-Ulcerorgenic Activity, Probiotic Potentials and Toxicological Evaluation of Fermented Unripe Musa  paradisiaca (Plantain) and Fermented Pentaclethra macrophylla (oil bean) seeds. TETFUND/ABSU/RP/2016/011. I. Elekwa., A.E. Ugbogu., F.O. Uhegbu., S.N. Umeham.
  2.    Effects of quarry Industry on the Physiochemical Status of Herbaceous Medicinal plants in Uturu, Abia State. TETFUND/ABSU/RP/2006/020. C.E. Ogbonna., A.E. Ugbogu., L.O. Obasi.
  3.  Biochemical, Bioactive and Toxicity Profiling of Two Delicious Wild Edible Mushrooms. TETFUND/ABSU/RP/2016/038.  E.I. Akubugwo., A.E. Ugbogu.



  1. Akubugwo, E. I., Obasi, N. A., Chinyere, G. C. and Ugbogu, A. E. (2007). Nutritional and chemical value of Amaranthus hybridus leaves from Afikpo, Nigeria. Afr. J Biotechnol., 6 (24): 2833 – 2839.


  1. Akubugwo, I. E. and Ugbogu, A. E. (2007). Physicochemical studies on oils from five selected Nigeria plants seeds. Pak J. Nutr., 6 (1): 75 – 78.


  1. Agbafor, K.N., Akubugwo, I.E. and Ugbogu, A.E. (2007). Toxicological evaluation of Okposi and Uburu salt Lake, Nigeria. J. Biotechhnol. Allied Sci., 2(2): 186 – 189.


  1. Akubugwo, E.I., Chinyere G.C. and Ugbogu, A.E. (2008). Comparative studies on oils from some common plant seeds in Nigeria. Pak J. , 7(4):570-573.


  1. Akubugwo, E.I., Obasi, N.A., Chinyere, G.C. and Ugbogu, A.E. (2008).Mineral and phytochemical contents in leaves of Amaranthus Hybridus and Solanum nigrum L. subjected to different processing methods. Afr. J. Biochem Res., 2(2):040-044.


  1. Chinyere G.C., Akubugwo E.I., Nwaukwa I.C. And Ugbogu, A.E. (2009). Nutritive value of Lagenaria sphaerica seed (Wild Bottle Gourds) from South-Eastern Nigeria. Pak J. , 8(3):384-387.


  1. Akubugwo, E.I., Ogbuji, G.C., Chinyere G.C. and Ugbogu, A.E. (2009). Physicochemical properties and enzyme activity studies in a refined oil contaminated soil in Isiukwuato, Abia State Nigeria. Nig. Soc. Exp Bio., 21: 79-84.


  1. Akubugwo, E.I., Ugbogu, O.C., Muoha, I.A. and Ugbogu, A.E. (2009). Impact of palm oil mill effluent (POME) on soils in Isialangwa, Abia State, Nigeria. Ecol., 27(4A):1677-1680.


  1. Akubugwo, I.E., Ofoegbu, C.J., Dike, C.C. and Ugbogu, A.E. (2010). Effect of mining operations on the physicochemical properties of soil from Ishiagu, Ebonyi State, Nigeria. Applied Environ. Sci., 6(1): 46 – 51.


  1. Akubugwo, E.I., Obasi, N.A., Chinyere, G.C., Eze, E., Nwokeoji, O. and Ugbogu, A.E. (2012). Phytoaccumulation effect of Amaranthus hybridus L grown on buwaya refuse dumpsite in Chikun, Nigeria on heavy metals. J Biodiver Environ , .2 (5):10-17.


  1. Uhegbu, F. O., Chinyere, G.C., Ugbogu, A.E. and Nwoku, K.C. (2012). Studies on some biochemical effects of aqueous leaf Extract of Landolphia owerrience on albino rats. Res. Biol., 2(5): 410-417.


  1. Uhegbu, F.O., Chinyere, G.C., Ugbogu, A.E. and Nwoku, K.C (2012). Arsenic and chromium in sea foods from Niger Delta of Nigeria: A case study of Warri, Delta State. Bull Environ. Contam. Toxicol. DOI 10.1007/s00128-012-0667-y.


  1. Akubugwo E.I, Chinyere G.C, Uhebgu F.O., Ugbogu O.C. and Ugbogu A.E. (2012). Some biochemical changes in serum of male albino rats treated with aqueous leaf extract of phyllanthus Amarus. J. Applied Bio. Pharma Technol.,3(3).


  1. Ude, V.C., Uhegbu,F.O., Akubugwo, E.I., Ugbogu,O.C. and Ugbogu, A.E. (2012). Effect of selected well water sources at Ishiagu quarry site,Ebonyi State, Nigeria on basic haematological parameters in peripheral blood of albino rats. J. Biochem and Biotechnol., 1(7):194-197.


  1. Duru, M., Amadi, C., Ugbogu, A., Eze A. and Amadi, B. (2012). Phytochemical, vitamin and proximate composition of Dacryodes edulis fruit at different stages of maturation. Asian J. Plant Sci. and Res, 2 (4):437-441.


  1. Duru, M., Ugbogu, A., Amadi, B., Odika, P., Chima-Ezika, O., Anudike, J. and  Osuocha, K. (2012). Chemical constituents of Buchholzia coriacea Proceedings of the 35th Annual International Conference, Workshop & Exhibition of Chemical Society of Nigeria, 39-45.


  1. Ugbogu, A.E., Akubugwo, E.I., Iweala., Uhegbu F.O., Chinyere G.C. and Obasi N.A. (2013). Role of Phytochemicals in Chemoprevention of Cancer. J. Pharma and Chem. Sci., 2(2) 566-75.


  1. Obasi N.A, Akubugwo E.I, Kalu K.M, Ugbogu, A.E. and Okorie, U.C. (2013). Toxicological assessment of various metals on selected edible leafy plants of umuka and ubahu dumpsites in Okigwe of Imo State, Nigeria. Exp. Bio. Agric. Sci., 1(6):441-453.


  1. Chinyere, C., Obisike, E.S., Ugbogu, A.E. and  Osuocha, K.U. (2013). Studies on municipal solid wastes dumping on soil anions, cations and selected enzymes activities at Njoku sawmill waste dumpsite, Owerri municipal, Imo State, Nigeria. Ethiopian J Environ. Studies Managt., 6:774-783.


  1. Chinyere, G.C., Akubugwo, E.I. and Ugbogu, A.E. (2013). Effects of Altering Palm Oil and Cassava Mill Effluents pH before dumping on dumpsite soils physic-chemical parameters and selected enzyme activities. Biodiver. Environ. Sci., 3(4): 46-58.


  1. Uhegbu, F.O., Ugbogu, A.E.,  Nwoku, K.C. and Ude, V.C (2013).  Effect of soybean oil supplemented diet on fatty acid level and lipid profile of albino rats.  British J. Pharma. Toxicol., 4(4): 158-162.


  1. Amadi, B., Onuoha, N., Amadi, C., Ugbogu, A. and Duru, M. (2013). Elemental, amino acid and phytochemical constituents of fruits of three different species of eggplant. J. Med. and Aromatic Plants., 3(2), 200-203.


  1. Duru, M. K., Amadi, B.A., Amadi, C.T., Ugbogu A.E. and Onuoha, N. (2013). Assessment of “Nduduagworagwo”, a traditional recipe of Akokwa people in Ideato north L.G.A of Imo State, Nigeria on body weight and some biochemical parameters. Continental J. Food Sci. Technol., 7 (1): 15 – 21.


  1. Duru, M., Nwanekwu, K., Ugbogu, A., Joseph, A., Amadi, C. and Ujubuonu, P. (2013). Urine therapy and its effects on some biochemical parameters using rats. Continental J. Biomed. Sci., 7 (1): 12-17.


  1. Duru, M., Ugbogu, A. and Amadi, B. (2013). Effect of Solanum macrocarpon fruit on haematology, hepatic and renal function. Biochem., 1(2): 28-32.


  1. Duru, M.K.C., Amadi, B.A., Eze, A.E., Ugbogu, A.E. and Onuoha, N. (2013). In vivo studies of Solanum aethiopicum fruit on some biochemical parameters using rats. Chem Pharma Res, 5(2):1-4.


  1. Duru, M., Amadi, B., Eze, A. and Ugbogu, A.E. (2013). Evaluation of “mgbam” traditional food on haematological profile and some selected biochemical parameters following consumption. Elixir Food Sci., 64:19345-19349.


  1. Duru, M., Amadi, B., Ugbogu, A. and Onuoha, N. (2013). Effect of “Nduduagworagwo” traditional food on haematology, hepatic and renal function of rats. Asian J. Agric. Food Sci., 1(1):21-26.


  1. Uhegbu F.O, Ugbogu, A.E. and Nwoku, K.C. (2013). Effect of aqueous extract of pear seeds on some biochemical parameters in albino rats. J   Biochem., 2(1): 110-115.


  1. Ugbogu, E.A., Wippler, S., Euston, M., Kouwenhoven, E.N., De Brouwer, A.P., Schweizer, L.M. and Schweizer, M. (2013). The contribution of the nonhomologous region of Prs1 to the maintenance of cell wall integrity and cell viability. FEMS Yeast Res., 13, 291-301.


  1. Ugbogu, O.C., Onyeagba, R.A., Nwaugo, V.O., Ugbogu, A.E. and Ogbonna, C.E. (2013).  Physicochemical and microbiological quality of soils surrounding two man-made lakes in Abia State, Nigeria. ABSU J. Environ. Sci. Tech.


  1. Egejuru, O.,  Akubugwo, E.I.,  Ude, V.C, Ugbogu, O.C. and Ugbogu, A.E.  (2014). Evaluation of physicochemical properties, microbial loads and enzymes activity studies of agrochemicals on the Imo-River basin farm in Imo State Nigeria.  Int. J. Curr. Microbiol. App. Sci. 3(6):776-786.


  1. Duru, M., Amadi, B., Ugbogu, A.E. and Eze, A. (2014). Effect of “udu”,- an antimalarial herbal preparation on visceral organ weight and blood lipid profiles in wistar rats. JPCS., 8:1-7.


  1. Odika, P. C., Akubugwo, E.I. and Ugbogu, A.E. (2014). Assessment of Njaba River on biochemical parameters using rats. Intraspecific J. Biodiver. Environ. Sci., 1(1):001-013.


  1. Ugbogu, A. E. and Amadi, B. A. (2014). Biochemical composition of month beans (aconitifolia) and pidgeon pea (C.cajan). Intraspecific J Med Sci. Res., 1 (1): 001-008.


  1. Ogueri, C.C., Elekwa, I., Ude, V.C and Ugbogu, A.E. (2014). Effect of aqueous extract of guava (Psidium guajava) leaf on blood glucose and liver enzymes in alloxan induced diabetic rats. British J. Pharma. Res., 4(9): 1079-1087.


  1. Ugbogu, A.E., Akubugwo, E.I., Uhegbu, F.O., Chinyere, G.C., Ugbogu, O.C. and Oduse, K.A. (2014). Quality assessment profile of Jatropha curcas (L) seed oil from Nigeria. Inter Food Res J., 21(2): 735-741.


  1. Osuocha, K.U., Akubugwo, E.I., Chinyere, G.C. and Ugbogu A.E. (2015). Seasonal impact on physicochemical characteristics and enzymatic activities of Ishiagu quarry mining effluent discharge soils. J. Curr. Biochem. Res., 3(3): 55- 66.


  1. Ogodo, A. C., Ugbogu, O.C., Ugbogu, A.E. and Ezeonu, C.S. (2015). Production of mixed fruit (pawpaw, banana and watermelon) wine using Saccharomyces cerevisiae isolated from palmwine. SpringerPlus, 4:683.


  1. Ogbonna, C.E., Otuu, F.C., Iwueke N.T., Egbu, A. U. and Ugbogu, A.E. (2015). Biochemical properties of trees along Umuahia-Aba expressway, Nigeria. J. Environ. Biol., 5(4): 99-103.


  1. Ogbonna, C.E., Otuu, F.C., Ugbogu, O.C., Nwaugo, V.O. and Ugbogu, A.E. (2015). Public health implications of heavy metal contamination of plants growing in the lead- zinc mining area of Ishiagu, Nigeria. Bio. Env. Sci., 7(4) 76-86.


  1. Ogbonna, C.E., Enete, I.C., Ugbogu A.E. and Egbu, A.U. (2015). Air pollution tolerance index (APTI) of some plants in the Ishiagu Lead-Zinc mining area, South Eastern Nigeria. World J. Phytoremed. Earth Sci., 2(2):109-114.


  1. Ogbonna, C.E., Ugbogu, A.E., Otuu, F.C., Adinna, E.N. and Okeke, C.U. (2015). Phytoremediation potential of some plants in the Ishiagu Lead-Zinc mining area, Nigeria. World J. Phytoremediation Earth Sci., 2(2):99-108.


  1. Uhegbu, F.O., Imo, C. and Ugbogu, A.E. (2015). Some biochemical changes in serum of female albino rats administered aqueous extract of Piper guineense Schumach seeds. J. Biochem. Res. Rev., 8(1): 1-7.


  1. Uhegbu, F.O., Imo, C. and Ugbogu, A.E. (2015). Effect of aqueous extract of Piper guineense seeds on some liver enzymes, antioxidant enzymes and some hematological parameters in albino rats. J. Plant Sci. Eco., 1(4):167-171.


  1. Chinyere, G.C., Osuocha, K.U., Offor C.E. and Ugbogu A.E. (2016). Seasonal impact of cassava mill effluents (CME) on dumpsites physicochemical parameters and selected enzyme activities in Isuikwuato area, Abia State, Nigeria. J. Sci. Environ. Technol., 5 (3): 1787–1805.


  1. Osuocha, K.U., Akubugwo, E.I., Chinyere, G.C. and Ugbogu, A.E. (2016). Seasonal impact on phytoaccumulation potentials of selected edible vegetables grown in Ishiagu quarry mining effluent discharge soils. J. Environ. Sci. Technol., 10(1): 34-43.


  1. Ugbogu, O.C., Onyeagba, R.A., Ugbogu, A.E. and Nwaugo, V.O.  (2016).   Heavy metal levels and potential pathogens of surface water and sediments of two man-made lakes at Lokpa Umuchieze, Abia State Nigeria.   J. Environ. Biol., 6(1): 4-10.


  1. Ogbonna, C.E., Enete, C., Ugbogu, O.C., Okeke, C.U., Otuu, F.C. and Ugbogu, A.E.(2016). Oxidative stress potential of lead-zinc mining on selected plants growing in Ishiagu, Nigeria. Ethiopian J. Environ. Studies Managt., 9(3): 303-314.


  1. Ugbogu, A.E. and Ugbogu, O.C. (2016). A review of microbial protein production: Prospects and challenges. FUW Trends Sci. Technol. J., 1(1): 182-185.


  1. Ugbogu A.E., Okezie E., Uche-Ikonne C., Duru M. and Atasie O.C. (2016). Toxicity evaluation of the aqueous stem extracts of Senna alata in wistar rats.” J. Biomed. Res., 4(4): 80-86.


  1. Osuocha, K .U., Chukwu, E . C., Ugbogu, E.A., Atasie, O.C. and Ogbonna, C.E. (2016). Effects of quarry mining activities on the nutritional composition of edible vegetables in Ishiagu, Ebonyi State, Nigeria.   Exp. Biol. Agric. Sci., 4(5): 467-474.


  1. Ugbogu, E.A., Okezie, E., Elekwa, I., Uhegbu, F., Akubugwo, E., Chinyere, G.C., Ewuzie, F. and Ugorji, C.J. (2016). Toxicological assessment of the aqueous dried leaf extracts of Senna alata in wistar rats. Afr. J. Pharm. Pharmacol., 10(34): 709-717.


  1. Ugbogu, E. A., Wang, K., Schweizer, L. M. and Schweizer, M. (2016). Metabolic gene products have evolved to interact with the cell wall integrity pathway in Saccharomyces cerevisiae. FEMS Yeast Res,


  1. Ogbonna C.E., Ugbogu A.E., Otuu F.C., Mbaogu N. E. and Johnson A.R. (2017). Influence of Rock Quarrying Activities on the Physiochemical Characteristics of Selected Edible Fruit Trees in Uturu, Abia State, Nigeria.   Ecol. Environ Sci., 5(1): 1-9.


  1. Hernández, A., Kholif, A. E., Elghandour, M. M. M. Y., Camacho, L. M., Cipriano, M. M., Salem, A. Z. M., Cruz, H. and Ugbogu, E. A. (2017). Effectiveness of xylanase and Saccharomyces cerevisiae as feed additives on gas emissions from agricultural calf farms. Cleaner Prod., 148: 616-623.


  1. Ikpeazu, O.V., Elekwa, I., Ugbogu, A.E., Arunsi, U.O. and Uche-Ikonne, C. (2017). Preliminary evaluation of anti-ulcer potential of aqueous extract of fermented unripe Musa paradisiaca in wistar rats. 5(2):17-23.


  1. Ugbogu, A.E., Arunsi, U.O., Uche-Ikonne, O. O, Ude, V.C and Okezie, E. (2017). Antiulcerogenic potentials of fermented aqueous extract of Pentaclethra macrophylla(Benth) seeds.  J. Biomed. Res., 5(3):57-64.


  1. Okezie, E., Ugbogu A.E., Odungide, A.A. and Atani C. S. (2017). Proximate, antinutritional and mineral estimation of some selected consumed green vegetables in Afaha Eket, Akwa-Ibom State, Nigeria.  J. Food Sci. Technol., 5(5):182-191.


  1. Elekwa, I., Ugbogu, A.E., Okereke, S.C. and Okezie, E. (2017). A review of selected medicinal plants with potential health benefits in South-Eastern Nigeria. J. Pharma and Chem., 6(4):162-171.



Conference proceeding


  • Ugbogu, E.A., Schweizer, L.M. & Schweizer, M.(2016). Impairment of cell signalling in Saccharomyces cerevisiae as a result of suboptimal PRPP synthetase activity. The Allied Genetics Conference at Orlando, Florida, Volume: Y3121A. USA.
  • Ugbogu, E.A., Ude, V.C., Schweizer, L.M. & Schweizer, M.(2015). Mutation of PRS causes impaired cell wall integrity signaling in yeast and neuropathies in humansYeast, 32 (Supplement 1), S65-S65. Italy.
  • Ugbogu, E.A., Schweizer, L.M. & Schweizer, M. (2015). Mutation of PRS genes causes impairment of cell signaling in yeast and neurological disorders in humans. 7th NSBMB South-East Zonal Symposium. Abstract number NMPH-20. MOUAU.
  • Ugbogu, E. A., Schweizer, L. M. & Schweizer, M. (2014). PRS gene family – a means of linking primary metabolism and cell signalling? Genetic Society of America, Yeast Genetics Meeting, Seattle, Washington, USA.  July 29th – August 3rd, 2014. Abstract number 315C.
  • Schweizer, L. M., Ugbogu, E. A. & Schweizer, M. (2013). PRS gene family – a means of linking primary metabolism and cell signalling? Yeast, 30 (S1), S183. Germany.
  • Ugbogu, E. A. (2013). PRS gene family – a means of linking primary metabolism and cell signalling. School of Life Sciences PhD Conference, Heriot-Watt University.